ExperimentList
Experiment #30
Name:	Balagopalan-2010-1
pubmed	20610546 [primary-reference]
Host Organism:	in vitro (taxid: -1)
Interaction detection method:	Name: inferred by author psi-mi MI:0363 [identical object]
Participant identification method:	Name: predetermined psi-mi MI:0396 [identical object]
publication year	2010
author-list	Balagopalan et al.

InteractorList
Interactor #1
Name:	Lat: Linker for activation of T-cells family member 1 (gene name: LAT) (synonym: 36 kDa phospho-tyrosine adapter protein)
uniprot knowledge base	O43561-2 [identical object]
refseq	NP_001014987.1 [identical object]
ensembl	ENSG00000213658 [gene product]
Interactor Type:	Name: protein psi-mi MI:0326 [identical object]
Organism:	Human
Interactor #2
Name:	Plcg1: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (gene name: PLCG1) (synonym: Phosphoinositide phospholipase C-gamma-1)
uniprot knowledge base	P19174 [identical object]
refseq	NP_877963.1 [identical object]
ensembl	ENSG00000124181 [gene product]
Interactor Type:	Name: protein psi-mi MI:0326 [identical object]
Organism:	Human
Interactor #3
Name:	PIP3: 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate (synonym: PIP3)
chebi	CHEBI:16618 [identical object]
Interactor Type:	Name: small molecule psi-mi MI:0328 [identical object]

InteractionList
Interaction #4
Name:	Lat-Plcg1
intact	EBI-1245318 [identical object]
Experiments:	Balagopalan-2010-1
Participants:
Participant #11	Lat Biological Role: Name: unspecified role psi-mi MI:0499 [identical object] Experimental Role: Name: unspecified role psi-mi MI:0499 [identical object] Feature #50 phosphorylated residue () [ 132 .. 132 ] prerequisite-ptm Cellular compartment Name: plasma membrane gene ontology GO:0005886 [gene ontology term for cellular component]
Participant #12	Plcg1 Biological Role: Name: unspecified role psi-mi MI:0499 [identical object] Experimental Role: Name: unspecified role psi-mi MI:0499 [identical object]
Interaction Type:	Name: direct interaction psi-mi MI:0407
Interaction attributes:
cooperative mechanism	pre-assembly
affected interaction	Plcg1-PIP3
cooperative effect outcome	positive cooperative effect
pre-assembly response	configurational pre-organization
Interaction #5
Name:	Plcg1-PIP3
Experiments:	Balagopalan-2010-1
Participants:
Participant #13	Plcg1 Biological Role: Name: unspecified role psi-mi MI:0499 [identical object] Experimental Role: Name: unspecified role psi-mi MI:0499 [identical object]
Participant #14	PIP3 Biological Role: Name: unspecified role psi-mi MI:0499 [identical object] Experimental Role: Name: unspecified role psi-mi MI:0499 [identical object] Cellular compartment Name: plasma membrane gene ontology GO:0005886 [gene ontology term for cellular component]
Interaction Type:	Name: direct interaction psi-mi MI:0407
Interaction attributes:
cooperative mechanism	pre-assembly
affected interaction	Lat-Plcg1
cooperative effect outcome	positive cooperative effect
pre-assembly response	configurational pre-organization