ExperimentList
Experiment #10
Name: xu-2003-1
pubmed 12529174 [primary-reference]
Host Organism: in vitro (taxid: -1)
Interaction detection method:
Name: inferred by author
psi-mi MI:0363 [identical object]
Participant identification method:
Name: predetermined
psi-mi MI:0396 [identical object]
publication year 2003
author-list Xu et al.
Experiment #11
Name: hao-2005-1
pubmed 16209941 [primary-reference]
Host Organism: in vitro (taxid: -1)
Interaction detection method:
Name: inferred by author
psi-mi MI:0363 [identical object]
Participant identification method:
Name: predetermined
psi-mi MI:0396 [identical object]
publication year 2005
author-list Hao et al.

InteractorList
Interactor #1
Name: Skp2: S-phase kinase-associated protein 2 (gene name: SKP2)
uniprot knowledge base Q13309 [identical object]
refseq NP_005974.2 [identical object]
ensembl ENSG00000145604 [gene product]
Interactor Type:
Name: protein
psi-mi MI:0326 [identical object]
Organism: Human
Interactor #2
Name: Cks1: Cyclin-dependent kinases regulatory subunit 1 (gene name: CKS1B)
uniprot knowledge base P61024 [identical object]
refseq NP_001817.1 [identical object]
ensembl ENSG00000173207 [gene product]
Interactor Type:
Name: protein
psi-mi MI:0326 [identical object]
Organism: Human
Interactor #3
Name: p27Kip1: Cyclin-dependent kinase inhibitor 1B (gene name: CDKN1B)
uniprot knowledge base P46527 [identical object]
refseq NP_004055.1 [identical object]
ensembl ENSG00000111276 [gene product]
Interactor Type:
Name: protein
psi-mi MI:0326 [identical object]
Organism: Human

InteractionList
Interaction #4
Name: Skp2-Cks1
wwpdb 2ASS [identical object]
intact EBI-456369 [identical object]
Experiments: xu-2003-1 hao-2005-1
Participants:
Participant #6
Skp2
Biological Role:
Name: unspecified role
psi-mi MI:0499 [identical object]
Experimental Role:
Name: unspecified role
psi-mi MI:0499 [identical object]
Participant #7
Cks1
Biological Role:
Name: unspecified role
psi-mi MI:0499 [identical object]
Experimental Role:
Name: unspecified role
psi-mi MI:0499 [identical object]
Interaction Type:
Name: direct interaction
psi-mi MI:0407 [identical object]
Interaction attributes:
cooperative mechanism pre-assembly
affected interaction Skp2_Cks1-p27Kip1
cooperative effect outcome positive cooperative effect
pre-assembly response composite binding site formation
Interaction #5
Name: Skp2_Cks1-p27Kip1
wwpdb 2AST [identical object]
intact EBI-2001686 [identical object]
Experiments: xu-2003-1 hao-2005-1
Participants:
Participant #8
Skp2-Cks1
Biological Role:
Name: unspecified role
psi-mi MI:0499 [identical object]
Experimental Role:
Name: unspecified role
psi-mi MI:0499 [identical object]
Participant #9
p27Kip1
Biological Role:
Name: unspecified role
psi-mi MI:0499 [identical object]
Experimental Role:
Name: unspecified role
psi-mi MI:0499 [identical object]
Feature #21 phosphorylated residue () [ 187 .. 187 ]
prerequisite-ptm
Interaction Type:
Name: direct interaction
psi-mi MI:0407 [identical object]